
Latest Science News
Scientists Discover Tiny Self-Replicating RNA Shedding Light on Life's Origins
Researchers at MRC Laboratory of Molecular Biology identified QT45, a small RNA molecule that copies itself and its strand, supporting RNA world hypothesis for life's start. Its size allows spontaneous emergence, with team now aiming for full self-replication cycle.
Discovery implies life could arise on other planets.
Enzyme N4BP2 Identified as Trigger for Cancer's Chaotic DNA Rewiring
UC San Diego team found N4BP2 enzyme causes chromothripsis, shattering chromosomes in 25% of cancers, enabling tumor adaptation. Blocking N4BP2 reduced DNA destruction in cancer cells dramatically.
This offers a new target to slow cancer evolution and resistance.
Large-Scale Molecular Glue Breakthrough for Leukemia Treatment
Teams from CeMM and Scripps developed high-throughput method generating thousands of variants to find glues degrading ENL protein in leukemia cells. The compound selectively reduces leukemia growth via ubiquitin ligase recruitment.
Approach enables rational discovery of drugs for undruggable targets.
FDA Approves Optune Tumor Fields with Chemo for Pancreatic Cancer
US FDA approved Optune combined with chemotherapy for pancreatic cancer, expanding device-based treatments for this aggressive disease. This diversifies therapeutic options beyond traditional therapies.
Approval marks progress in oncology modalities.