Science

Latest Science News

đź“…December 19, 2025 at 1:00 AM
2025's top science breakthroughs include CRISPR therapies slashing cholesterol, antimatter production advances, exoplanet discoveries, and rapid Antarctic glacier retreat, plus innovations in cancer, heart disease, and dark energy.
1

CRISPR Gene Therapy Reduces LDL Cholesterol by 50% in Phase 1 Trial

A first-in-human trial of CRISPR therapy targeting ANGPTL3 safely lowered LDL cholesterol by nearly 50% and triglycerides by 55%. This November breakthrough could transform treatments for cardiovascular diseases.Source 1

2

CERN Achieves Eightfold Increase in Antimatter Production

Scientists at CERN's ALPHA experiment used laser-cooled beryllium ions to cool positrons to -266°C, producing over 15,000 antihydrogen atoms in under seven hours. This advance boosts antimatter research capabilities.Source 1

3

Hektoria Glacier in Antarctica Retreats Fastest in Modern History

Reported on 3 November, the glacier lost nearly 50% of its mass in just two months due to rapid disintegration. This highlights accelerating climate impacts on polar ice.Source 1

4

Tryptophan Confirmed on Asteroid Bennu

Analysis of NASA's OSIRIS-REx samples on 27 November verified the amino acid tryptophan, key for protein biosynthesis, on the asteroid. This supports theories of life's building blocks in space.Source 1

5

MIT Chemists Achieve First Complete Synthesis of Anticancer Verticillin A

On 2 December, researchers synthesized the fungal compound verticillin A, promising for aggressive brain tumors, first discovered over 50 years ago. This enables further drug development.Source 1

6

New ViViD-AFM Microscopy Reveals Influenza Virus Invasion

ETH Zurich demonstrated on 4 December a technique combining atomic force and fluorescence microscopy for high-resolution views of influenza invading human cells. This could advance antiviral research.Source 1

7

GPR133 Receptor Boosts Bone Strength, Reverses Osteoporosis in Mice

Leipzig University experts identified GPR133 on 8 September; stimulating it with AP503 enhanced bone strength even in osteoporosis models. This offers new osteoporosis treatment potential.Source 1

8

UC Berkeley Maps Brain Circuits for Sleep-Regulated Growth Hormone

Researchers uncovered a feedback loop where sleep triggers growth hormone release, which regulates wakefulness, linking poor sleep to obesity and diabetes. This opens paths for metabolic disorder treatments.Source 1

9

UCL Gene Therapy Reverses Incurable Blood Cancer in Children

A base-editing CRISPR therapy by UCL and Great Ormond Street Hospital successfully treated previously incurable blood cancers in some children. This caps a year of medical advances.Source 2

10

DESI Results Suggest Dark Energy May Be Weakening

UCL-involved Dark Energy Spectroscopic Instrument data indicates dark energy, driving cosmic expansion, might be diminishing, challenging models and hinting at a 'big crunch' universe end.Source 2

11

Stanford Study Eradicates Liver Tumors in Mice via Immune Activation

Blocking erythropoietin turned immune-resistant liver tumors 'hot,' and combined with immunotherapy, led to complete regression in most mice. This advances cancer immunotherapy.Source 3

12

New Antihypertensive Drugs and Blood Pressure Control Reduce Dementia Risk

2025 research highlighted benefits of blood pressure management, the top preventable heart disease risk, also lowering dementia odds per American Heart Association reviews.Source 5