Latest Science News
AI and Physics-Based Modeling Identifies New Parkinson’s Drug
Gain Therapeutics' GT-02287, an allosteric modulator of glucocerebrosidase (GCase), restores enzyme function in preclinical Parkinson's models, reducing neuroinflammation and neurodegeneration. The Magellan platform uses AI and structural modeling to target allosteric sites. Phase 1b results expected Q4 2025, with Phase 2 in 2026.
New Discovery Offers Hope for Friedreich's Ataxia
Researchers found lowering FDX2 levels compensates for frataxin loss by restoring iron-sulfur cluster production in cells. Using worm models under hypoxia, mutations in FDX2 and NFS1 enabled survival in normal oxygen. Verified in mouse and human cells, suggesting druggable targets.
Brain Switch ΔFosB Could Rewrite Mental Illness Treatment
ΔFosB accumulates in reward circuits during stress or drug exposure, causing long-term gene expression changes linked to addiction and mood disorders. Findings from animal and human brain studies highlight its role in vulnerability. Supports resilience-focused therapies.
First X-Ray Image of Interstellar Comet 3I/ATLAS
Comet 3I/ATLAS shows unique X-ray emissions unseen in prior interstellar objects, captured ahead of its Earth close encounter on December 19. New NASA/ESA images reveal increasing activity. Adds to 2025's space surprises.
Biggest Breakthroughs in Cell Biology 2025
Key advances include microglia reprogramming, immune cell diagnostics, long-read sequencing for epigenomics, and CRISPR therapies for ALS. Highlights also feature stellar spatial biology and dark genome illumination for therapeutics.
CERN Solves Deuteron Formation Mystery
TUM researchers at CERN uncovered how deuterons form, resolving a decades-old particle physics puzzle through groundbreaking experiments.
Uranus and Neptune Rockier Than Expected
New findings reveal Uranus and Neptune may have far more rocky interiors than previously thought, challenging existing models of ice giants.
Morning Cancer Immunotherapy Boosts Survival
Scheduling immunotherapy for small-cell lung cancer in the morning reduced death risk by up to 63% in a patient study.
Largest Spinning Dark Matter Filament Discovered
Astronomers found a 50-million-light-year dark matter filament, the universe's largest spinning structure, with co-rotating galaxies inside.
New Supermassive Black Hole from Early Universe
A supermassive black hole observed 500 million years post-Big Bang challenges formation theories; 2025 also saw black hole mergers proving Hawking's predictions.
Breakthrough 3D Wiring for 10,000-Qubit Quantum Processors
New 3D architecture enables scalable quantum computing with 10,000-qubit processors.
Earliest Evidence of Human Fire-Making Discovered
Archaeologists uncovered the oldest signs of controlled fire use by early humans.