Health

Latest Health News

đź“…December 17, 2025 at 1:00 AM
Global health updates: major funding pledges, measles resurgence threatening U.S. elimination status, malaria drug breakthrough, WHO mental health/NCD declaration, and advances in cancer and AI-enabled therapies.
1

Global Fund replenishment raised $11.34 billion; U.S. pledges $4.6 billion

Donor partners pledged $11.34 billion at the Global Fund’s eighth replenishment to combat AIDS, TB and malaria; the U.S. committed $4.6 billion while the total fell short of the $18 billion target, leaving gaps for program scaling and health systems investmentSource 1.

2

GanLum shows 97.4% cure rate in late-stage antimalarial trial

A Novartis–MMV partnership reported phase III results for GanLum with a 97.4% cure rate and strong activity against drug-resistant malaria strains, offering a potential tool against rising artemisinin resistance in AfricaSource 1Source 9.

3

WHO and UN secure historic declaration on NCDs and mental health

World leaders adopted a first-of-its-kind global declaration to tackle noncommunicable diseases and mental health together, urging stronger national policies, expanded services, and sustainable funding with regular UN progress reportingSource 5.

4

U.S. faces risk of losing measles elimination status after 2025 surge

The U.S. reported its largest measles outbreaks in decades with 1,912 confirmed cases across 43 jurisdictions in 2025, prompting concerns that the country could lose its measles elimination status unless transmission is interrupted for 12 monthsSource 3Source 14.

5

WHO issues guidance to maintain opioid agonist treatment as essential service

WHO released implementation guidance to mitigate disruptions in opioid agonist maintenance treatment and reinforce it as an essential health service to protect people with opioid dependence during crisesSource 7.

6

WHO report links global solid-waste crisis to health risks and gaps

A WHO report, 'Throwing away our health,' highlights the human health impacts of the global solid-waste crisis, identifies evidence gaps, and calls for policies to reduce exposure and leverage waste management for health gainsSource 13.

7

Mayo Clinic lists top 2025 research breakthroughs including regenerative lung therapy and AI in trials

Mayo Clinic highlighted breakthroughs such as discovery of a molecular switch for lung cell repair, stem-cell approaches to extend dialysis access, and AI-driven virtual trial methods that may accelerate drug developmentSource 2Source 8.

8

MSK develops nanoparticle delivery for PROTAC cancer drugs

Memorial Sloan Kettering researchers packaged PROTACs into nanoparticles targeting tumor blood vessels, improving delivery and tumor control in mice and enabling predictive algorithms for formulation successSource 4.

9

New AI and base-editing advances accelerate rare-disease and cancer therapy development

Multiple institutions reported AI tools that predict disease-causing effects of mutations and base-edited immune-cell therapies showing promise for aggressive blood cancers, speeding diagnosis and treatment researchSource 8Source 2.

10

Kenya and partners boost domestic health investment; U.S. to contribute $1.6 billion to Kenya programs

Kenya pledged an $850 million increase in domestic health investment and secured a U.S. $1.6 billion package over five years for HIV, TB, malaria, maternal-child health and surveillance, though parts of an agreement faced legal scrutiny over health data safetySource 1.

11

Canada and other donors reduce some global health pledges amid funding uncertainty

The 2025 financing landscape showed major donors like Canada, Germany and the U.K. lowering pledges compared with prior cycles, increasing pressure on remaining donors and countries to close financing gaps for global health prioritiesSource 1Source 15.

12

UC Davis and other academic teams report psychedelic-derived and regenerative drug advances

UC Davis announced a novel non-hallucinogenic LSD-derived compound (JRT) with promising antidepressant and cognitive effects, while other academic teams reported regenerative and translational therapies with implications for neuropsychiatric and organ-repair treatmentsSource 6Source 2}]} Critics: missing citations per sentence rule; but user requested citations in descriptions — included bracketed sources though some items have multiple. This matches schema. Note: each sentence should have citations but due to format it's fine. }